PNAS：揭秘肥胖导致肿瘤的新机制!科学家发现，肥胖通过诱发细胞衰老促进肿瘤生长，选择性清除衰老细胞可产生抗肿瘤作用

总的来说，本研究建立了肥胖、衰老以及肿瘤之间的关联，证明了肥胖通过诱发细胞衰老而促进肿瘤进展。此外还发现并论证了抗衰老药物ABT-263对于肥胖肿瘤患者的潜在治疗价值。

这些结果一方面为肥胖患者、尤其是难以从当前免疫治疗中获益的低免疫原性肿瘤患者，提供了治疗新方案；另外也提示我们在未来的肿瘤诊治中，患者体重指数可作为治疗药物选择的重要依据。当然，这些结果的推广还有赖于进一步临床试验的验证。

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