《细胞·代谢》:肠癌“氨”杀T细胞! |
![]() |
参考文献
[1]Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71(3):209-249. doi:10.3322/caac.21660
[2]Holt PR, Kozuch P, Mewar S. Colon cancer and the elderly: from screening to treatment in management of GI disease in the elderly. Best Pract Res Clin Gastroenterol. 2009;23(6):889-907. doi:10.1016/j.bpg.2009.10.010
[3]Biller LH, Schrag D. Diagnosis and Treatment of Metastatic Colorectal Cancer: A Review. . 2021;325(7):669-685. doi:10.1001/jama.2021.0106
[4]Araghi M, Arnold M, Rutherford MJ, et al. Colon and rectal cancer survival in seven high-income countries 2010-2014: variation by age and stage at diagnosis (the ICBP SURVMARK-2 project). Gut. 2021;70(1):114-126. doi:10.1136/gutjnl-2020-320625
[5]Brahmer JR, Drake CG, Wollner I, et al. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol. 2010;28(19):3167-3175. doi:10.1200/JCO.2009.26.7609
[6]Spinelli JB, Yoon H, Ringel AE, Jeanfavre S, Clish CB, Haigis MC. Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass. Science. 2017;358(6365):941-946. doi:10.1126/science.aam9305
[7]Bell HN, Huber AK, Singhal R, et al. Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer [published online ahead of print, 2022 Dec 12]. Cell Metab. 2022;S1550-4131(22)00504-6. doi:10.1016/j.cmet.2022.11.013
医药网新闻
- 相关报道
-
- 中科微智斩获2025中国肠道大会"益生菌实力企业",MGBlab引领菌肠脑研究新范式 (2025-06-09)
- 首款国产冠脉负压机械抽吸导管获批 (2025-06-09)
- Cell:粪菌移植的安全性受质疑,或产生长期、意料之外的负面健康后果 (2025-06-08)
- 青稞酰化黄酮α (2025-06-08)
- 89.5%改善率!NCR201细胞疗法实现帕金森病“关期”消失 (2025-06-08)
- 2025 ASCO:CheckMate 816/77T携两大LBA,试图解答能不能做“精准辅助治疗” ! (2025-06-07)
- Immunity:细菌抗肿瘤免疫疗法有益和有害作用的细胞机制 (2025-06-07)
- 程颖教授解读ES (2025-06-07)
- Nature:大脑不再是“免疫孤岛”!肠道、脂肪竟是T细胞的“大脑信使” (2025-06-07)
- 智康医疗突破性研究:基于血流动力学的颅内动脉瘤破裂风险评估 (2025-06-06)
- 视频新闻
-
- 图片新闻
-
医药网免责声明:
- 本公司对医药网上刊登之所有信息不声明或保证其内容之正确性或可靠性;您于此接受并承认信赖任何信息所生之风险应自行承担。本公司,有权但无此义务,改善或更正所刊登信息任何部分之错误或疏失。
- 凡本网注明"来源:XXX(非医药网)"的作品,均转载自其它媒体,转载目的在于传递更多信息,并不代表本网赞同其观点和对其真实性负责。本网转载其他媒体之稿件,意在为公众提供免费服务。如稿件版权单位或个人不想在本网发布,可与本网联系,本网视情况可立即将其撤除。联系QQ:896150040