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《转化精神病学》:四季流转如何影响大脑功能?

了解大脑的季节适应性与预防和治疗精神疾病密切相关。虽然我们已经进行了一些推测和猜想,但是季节变化对精神疾病的影响还远没有得到充分研究,还需要更严谨的神经影像学检查、更深思熟虑的试验设计、更多的样本量和更高分辨率的环境表征来探究其中的机制。

最后,私心加一句,春乏秋困夏打囤这个事儿,它真的是不赖我啊!

参考文献:

[1]Kurata Y, Izawa S, Nomura S. Seasonality in mood and behaviours of Japanese residents in high-latitude regions: transnational cross-sectional study[J]. BioPsychoSocial Medicine, 2016, 10: 1-12.

[2]Zhang R, Volkow N D. Seasonality of brain function: role in psychiatric disorders[J]. Translational Psychiatry, 2023, 13(1): 65.

[3]Cassidy F, Carroll B J. Seasonal variation of mixed and pure episodes of bipolar disorder[J]. Journal of affective disorders, 2002, 68(1): 25-31.

[4]Lambert G W, Reid C, Kaye D M, et al. Effect of sunlight and season on serotonin turnover in the brain[J]. The Lancet, 2002, 360(9348): 1840-1842.

[5]Aumann T D, Raabus M, Tomas D, et al. Differences in number of midbrain dopamine neurons associated with summer and winter photoperiods in humans[J]. PloS one, 2016, 11(7): e0158847.

[6]Neumeister A, Willeit M, Praschak-Rieder N, et al. Dopamine transporter availability in symptomatic depressed patients with seasonal affective disorder and healthy controls[J]. Psychological medicine, 2001, 31(8): 1467-1473.

[7]Hofman M A, Swaab D F. Diurnal and seasonal rhythms of neuronal activity in the suprachiasmatic nucleus of humans[J]. Journal of biological rhythms, 1993, 8(4): 283-295.

[8]Kasper S, Wehr T A, Bartko J J, et al. Epidemiological findings of seasonal changes in mood and behavior: a telephone survey of Montgomery County, Maryland[J]. Archives of general psychiatry, 1989.

[9]Figueiro M G, Rea M S. Evening daylight may cause adolescents to sleep less in spring than in winter[J]. Chronobiology International, 2010, 27(6): 1242-1258.

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