热门解读|Claudin 18.2 |
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参考文献
1. Tsukita, S., Furuse, M. Itoh, M. Multifunctional strands in tight junctions. Nat Rev Mol Cell Biol 2, 285-293, doi:10.1038/35067088 (2001).
2. Gunzel, D. Yu, A. S. Claudins and the modulation of tight junction permeability. Physiol Rev 93, 525-569, doi:10.1152/physrev.00019.2012
93/2/525 [pii] (2013).
3. Klamp, T. et al. Highly specific auto-antibodies against claudin-18 isoform 2 induced by a chimeric HBcAg virus-like particle vaccine kill tumor cells and inhibit the growth of lung metastases. Cancer Res 71, 516-527, doi:10.1158/0008-5472.CAN-10-2292 (2011).
4. Sahin, U. et al. Claudin-18 splice variant 2 is a pan-cancer target suitable for therapeutic antibody development. Clinical cancer research : an official journal of the American Association for Cancer Research 14, 7624-7634, doi:10.1158/1078-0432.CCR-08-1547 (2008).
5. Sanada, Y. et al. Down-regulation of the claudin-18 gene, identified through serial analysis of gene expression data analysis, in gastric cancer with an intestinal . J Pathol 208, 633-642, doi:10.1002/path.1922 (2006).
6. Woll, S. et al. Claudin 18.2 is a target for IMAB362 antibody in pancreatic neoplasms. Int J Cancer 134, 731-739, doi:10.1002/ijc.28400 (2014).
7. Micke, P. et al. Aberrantly activated claudin 6 and 18.2 as potential therapy targets in non-small-cell lung cancer. Int J Cancer 135, 2206-2214, doi:10.1002/ijc.28857 (2014).
8. Moentenich, V. et al. Claudin 18.2 expression in esophageal adenocarcinoma and its potential impact on future treatment strategies. Oncol Lett 19, 3665-3670, doi:10.3892/ol.2020.11520 (2020).
9. Arnold, A. et al. Prognostic impact of Claudin 18.2 in gastric and esophageal adenocarcinomas. Clin Transl Oncol, doi:10.1007/s12094-020-02380-0 (2020).
10. Singh, P., Toom, S. Huang, Y. Anti-claudin 18.2 antibody as new targeted therapy for advanced gastric cancer. J Hematol Oncol 10, 105, doi:10.1186/s13045-017-0473-4 (2017).
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